Articles
Milk and Dairy Products
| Title | Effects of Processing Conditions During Manufacture on Retronasal-Aroma Compounds from a Milk Coffee Drink |
| Author | M.Ikeda, M.Akiyama, Y.Hirano, K.Miyazi, M.Kono*1, Y.Imayoshi*1, H.Iwabuchi*1, T.Onodera*2, and K.Toko*2 *1 San-Ei Gen F.F.I., Inc., *2Kyushu Univ. |
| Journal | Journal of Food Science 83(3): 605-616 (2018) |
| Summary | Regarding the manufacture of a ready-to-drink (RTD) milk coffee that retained original volatile characteristics, an investigation of retronasal-aroma compounds from an RTD milk coffee revealed that a new process without pH adjustment of coffee was superior to a conventional process with the pH adjustment. |
Nutrition
| Title | Potential Role of Amino Acid/Protein Nutrition and Exercise in Serum Albumin Redox State |
| Author | Y.Wada, Y.Takeda, and M.Kuwahata* *Departments of Nutrition Science, Graduate School of Life and Environmental Sciences, Kyoto Prefectural University |
| Journal | Nutrients, 10(1), Art.17 (2018) |
| Summary | This article extensively reviews serum albumin and the redox state of albumin in the context of amino acid/protein nutritional status and exercise training. |
Bifidobacteria and Intestinal Flora
| Title | Degradation of food-derived opioid peptides by Bifidobacteria |
| Author | T.Sakurai, A.Yamada, N.Hashikura, T.Odamaki, JZ.Xiao |
| Journal | Beneficial Microbes 9(4): 675-682 (2018) |
| Summary | We found that, some B. longum subsp. infantis and B. bifidum strains had a degradative activity in food-derived opioid peptides, which have been reported to cause diseases, such as gastrointestinal inflammation, celiac disease, and mental disorders. |
| Title | Effects of Bifidobacterium breve B-3 on body fat reductions in pre-obese adults: A randomized, double-blind, placebo-controlled trial |
| Author | J.Minami, N.Iwabuchi, M.Tanaka, K.Yamauchi, J.Xiao, F.Abe, and N.Sakane* *National Hospital Organization Kyoto Medical Center |
| Journal | Bioscience of Microbiota, Food and Health 37(3): 67-75(2018) |
| Summary | The effects of the consumption of Bifidobacterium breve B-3 on body fat reduction in healthy pre-obese (25 ≤ BMI < 30) adults were investigated in a double-blind, placebo-controlled trial. Body fat mass was significantly lower in the B-3 group than in the placebo group. Waist circumference in the B-3 group was significantly lower at week 12 than at the baseline. |
| Title | Genomic diversity and distribution of Bifidobacterium longum subsp. longum across the human lifespan |
| Author | T.Odamaki, F.Bottacini*, K.Kato, E.Mitsuyama, K.Yoshida, A.Horigome, JZ.Xiao, and D.van Sinderen* *APC Microbiome Institute and School of Microbiology, National University of Ireland |
| Journal | Scientific Reports 8(1): Art. 85 (2018) |
| Summary | We performed a comparative genome analysis of Bifidobacterium longum subsp. longum to unravel the reason why this subspecies are widely distributed across all generation. As results, a broad distribution of them across the human lifespan is due to a high transfer level between family members. We furthermore identified a variety of genes which could enhance their adaptation and increase competitiveness in the gut environment, enriched in genomes corresponding to specific ages. |
| Title | Therapeutic potential of Bifidobacterium breve strain A1 for preventing cognitive impairment in Alzheimer's disease |
| Author | Y.Kobayashi, H.Sugahara, K.Shimada*1, E.Mitsuyama, T.Kuhara, A.Yasuoka*1, T.Kondo*1, K.Abe*1,2 and JZ.Xiao *1Group for Food Functionality Assessment, Kanagawa Institute of Industrial Science and Technology, *2Department of Applied Biological Chemistry, Graduate School of Agricultural and Life Sciences, The University of Tokyo |
| Journal | Scientific Reports 7(1):13510 (2017) |
| Summary | We focused on gut-microbiota-brain axis and found that oral administration of Bifidobacterium breve A1 to Alzheimer's disease model mice improved cognitive dysfunction through suppressing the expression of inflammation and immune-reactive genes. |
Functional Ingredients
| Title | Investigation of potent odorants generated during the production |
| Author | H.Nakada, M.Ohata*1,2, M.Hosaka*1, H.Ochi, F.Abe, and K.Arihara*1 *1Kitasato University, *2Nihon University |
| Journal | Animal Science Journal 89(9):1348-1354(2018) |
| Summary | We evaluated predominant odorants of Whey protein hydrolysates(WPH), and our results showed that difference of odor characteristics between whey protein concentrate(WPC) and WPH, and three odor-active compounds contributed to the odor of WPH. Additionally, this study suggests that specific free amino acids are important precursors for generation of these compounds in manufacturing process of WPH. |
| Title | Antihypertensive effect of the casein-derived peptide Met-Lys-Pro in individuals with high-normal blood pressure or grade 1 hypertension-A randomized, double-blind, placebo-controlled, parallel-group trial- |
| Author | N.Yuda, M.Tanaka, A.Yamada, D.Ochi, K.Yamauchi, F.Abe, and N.Sakane* *National Hospital Organization Kyoto Medical Center |
| Journal | Japan Pharmacology & Therapeutics 46(4):529-37(2018) |
| Summary | Antihypertensive effect of the casein-derived peptide Met-Lys-Pro (MKP) was confirmed by clinical trial. Daily MKP ingestion is a effective systolic blood pressure lowering treatment for people with mildly high blood pressure. |
| Title | Phytosterols derived from Aloe Vera (Aloe sterol) supplementation prevents skin photoaging acceration by estrogen deficiency. |
| Author | M.Saito, Z.Yao, M.Tanaka, E.Misawa, K.Yamauchi, and F.Abe |
| Journal | FRAGRANCE JOURNAL 45(12): 29-36 (2017) |
| Summary | We have showed that Aloe sterol improving skin dryness in a clinical trial and the anti-photoaging effect in estrogen deficiency model. This review described these results and the usefulness of Aloe sterol supplementation for skin beauty. |
| Title | Blood pressure-lowering effects of casein-derived peptide met-lys-pro in subjects with high-normal blood pressure and grade 1 hypertension - A randomized, double-blind, placebo-controlled, parallel-group, trial- |
| Author | D.Ochi, A.Yamada, K.Yamauchi, F.Abe, and Y.Tho* *Aiwa Clinic, Latvia |
| Journal | Japanese pharmacology & therapeutics 45(10): 1637-1648 (2017) |
| Summary | We evaluated the effect of Met-Lys-Pro（MKP） in lowering blood pressure in subjects with high-normal blood pressure and grade 1 hypertension in a randomized, double-blind, placebo-controlled, parallel-group trial for 12 weeks. The result showed that 100 μg MKP has a beneficial effect on lowering systolic and diastolic blood pressure. |
| Title | Effects of lactoferrin and lactoperoxidase-containing food on the oral microbiota of older individuals |
| Author | M.Nakano, H.Wakabayashi, H.Sugahara, T.Odamaki, K.Yamauchi, F.Abe, JZ.Xiao, K.Murakami*, K.Ishikawa*, and S.Hironaka* *Department of Special Needs Dentistry, Division of Hygiene and Oral Health, Showa University School of Dentistry |
| Journal | Microbiology and Immunology 61(10): 416-426 (2017) |
| Summary | The long-term ingestion of lactoferrin and lactoperoxidase-containing tablets promotes a shift from a gram-negative-dominated unhealthy community to a gram-positive-dominated healthy community in the oral microbiota. |